Test Your Hereditary Angioedema (HAE) Knowledge
Reviewed by: HU Medical Review Board | Last reviewed: June 2026 | Last updated: June 2026
Hereditary angioedema (HAE) is rare, frequently misdiagnosed, and changing quickly on the treatment side. This 5-question challenge spans laboratory workup, the bradykinin-mediated mechanism, diagnostic subtyping, on-demand management principles, and a common safety consideration. See how your current understanding lines up with guideline consensus.
Clinical Challenge
A patient with confirmed HAE asks which of their attacks are worth treating. Per guideline consensus, which approach is correct?
Clinical Challenge
Which initial laboratory test is the recommended screening test when HAE due to C1 inhibitor (C1-INH) deficiency is suspected?
Clinical Challenge
Recurrent angioedema that occurs without urticaria and does not improve with antihistamines, corticosteroids, or epinephrine most strongly points to which underlying mechanism?
Clinical Challenge
In HAE due to C1-INH deficiency, which laboratory pattern characterizes type II disease?
Clinical Challenge
Which commonly prescribed medication class should generally be avoided in patients with HAE because it can precipitate or worsen angioedema?